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 <title>PL-100</title>
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 <title>Merck puts HIV development program on hold</title>
 <link>http://www.fiercebiotech.com/story/merck-puts-hiv-development-program-hold/2008-07-28?utm_medium=rss&amp;utm_source=rss&amp;cmp-id=OTC-RSS-FB0</link>
 <description>&lt;p&gt;Canada&#039;s Ambrilia Biopharma says that Merck has placed the development program for the HIV therapy--MK-8122--on hold as it focuses on &lt;a href=&quot;http://www.fiercebioresearcher.com/vaccines/story/feds-steering-funds-back-to-basic-aids-vax-research/2008-03-27&quot;&gt;basic science efforts&lt;/a&gt;&amp;nbsp;to evaluate other PL-100 prodrugs and formulation options. Ambrilia says that Merck is also exploring possible back-up compounds.&lt;/p&gt;
&lt;p&gt;&quot;Ambrilia believes in the potential of PPL-100/MK-8122 and related compounds to offer advantages to HIV patients over the currently commercialized protease inhibitors,&quot; said Dr. Philippe Calais, the CEO of Ambrilia. &quot;Our &lt;a href=&quot;http://www.fiercebiotech.com/story/ambrilia-inks-232m-licensing-deal-of-hiv-drug/2006-10-12?utm_medium=rss&amp;amp;utm_source=rss&amp;amp;cmp-id=OTC-RSS-FB0&quot;&gt;partnership with Merck&lt;/a&gt; continues and we look forward to further progress on potential back-up compounds.&quot; Dr. Calais continued, &quot;Both companies remain focused on the partnership and determined to provide the best compounds available to help people with HIV/AIDS.&quot;&lt;/p&gt;
&lt;p&gt;- check out the &lt;a href=&quot;http://www.fiercebiotech.com/press-releases/ambrilia-provides-update-ppl-100-partnership-merck&quot;&gt;release&lt;/a&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Related Articles:&lt;br /&gt;&lt;/strong&gt;&lt;a href=&quot;http://www.fiercebiotech.com/story/ambrilia-inks-232m-licensing-deal-of-hiv-drug/2006-10-12?utm_medium=rss&amp;amp;utm_source=rss&amp;amp;cmp-id=OTC-RSS-FB0&quot;&gt;Ambrilia inks $232M licensing deal of HIV drug&lt;/a&gt;&lt;br /&gt;&lt;a href=&quot;http://www.fiercebioresearcher.com/vaccines/story/aids-vaccine-researchers-years-away-from-success/2008-04-24&quot;&gt;AIDS vaccine researchers years away from success&lt;/a&gt;&lt;br /&gt;&lt;a href=&quot;http://www.fiercebioresearcher.com/vaccines/story/feds-steering-funds-back-to-basic-aids-vax-research/2008-03-27&quot;&gt;Feds steering funds back to basic AIDS vax research&lt;/a&gt;&lt;br /&gt;&lt;a href=&quot;http://www.fiercebiotech.com/press-releases/press-release-merck-halts-study-ineffective-hiv-vaccine?utm_medium=nl&amp;amp;utm_source=internal&quot;&gt;Merck halts study of &quot;ineffective&quot; HIV vaccine&lt;/a&gt;&lt;/p&gt;</description>
 <comments>http://www.fiercebiotech.com/story/merck-puts-hiv-development-program-hold/2008-07-28#comments</comments>
 <category domain="http://www.fiercebiotech.com/tags/ambrilia-biopharma">Ambrilia Biopharma</category>
 <category domain="http://www.fiercebiotech.com/tags/hiv">HIV/AIDS</category>
 <category domain="http://www.fiercebiotech.com/tags/merck">Merck</category>
 <category domain="http://www.fiercebiotech.com/tags/pl-100">PL-100</category>
 <pubDate>Mon, 28 Jul 2008 11:30:24 -0400</pubDate>
 <dc:creator>John Carroll</dc:creator>
 <guid isPermaLink="false">31718 at http://www.fiercebiotech.com</guid>
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