ALSO NOTED: GSK cuts 5,000 jobs; Codexis opens Singapore lab; Reliant sets IPO terms;and much more...

> The closure of a GlaxoSmithKline's Puerto Rican plant has kicked off the plan to cut 5,000 jobs. Report

> Codexis has opened a laboratory in Singapore, its first research facility in Asia. Release

> Reliant Pharmaceuticals has set its IPO terms at $25 to $27 a share. The company has raised more than $500 million from investors. Report

> Pharmion Corporation and MethylGene have reported preliminary clinical data from the Companies' MGCD0103 Phase I/II combination trial with Gemzar. Release

> It's official: the UK's National Health Service will start using Johnson & Johnson's Velcade under an unprecedented money-back-guarantee program. Report

> Bristol-Myers Squibb's third-quarter results show what one big drug can do. Net income more than doubled to $858 million on revenues of $5.1 billion--and Plavix was the biggest reason. Report

> The European Union backed a trade protocol that will give poor countries better access to cheap generics in the event of an epidemic. Report

> The FDA slapped a new warning on Provigil, a drug for narcolepsy and other sleeping disorders made by Cephalon. Report

And Finally… Most people believe their sleep meds work better than the drugs actually do. Article