Research associate, Metabolism - Dicerna

Position Description

Dicerna Pharmaceuticals is a private, venture-backed biopharmaceutical company developing novel therapeutic agents in multiple therapeutic areas based on its proprietary Dicer Substrate Technology™, which triggers RNA interference (RNAi) in a potent and specific manner.

Job description:

The successful candidate will be a self-motivated bench scientist with a fundamental understanding of experimental design. Responsibilities will include both in vitro and in vivo assay development pertaining to specific therapeutic gene targets, summarization of experimental results, and written/oral reportage of findings. An ability to interact in a dynamic start-up R&D team environment is essential. Knowledge of key therapeutic areas such as obesity, diabetes and dyslipidemia is a plus.

Background and skill requirements:

• The candidate should have a B.S. or M.S. degree with at least 2-3 years of industry experience.
• Cell culture technique
• Light and fluorescent microscopy
• PCR, quantitative RT-PCR and protocol optimization
• DNA, RNA and protein isolation from both cultured cells and animal tissues
• DNA and protein gel electrophoresis
• Protein immunoblotting
• siRNA gene knockdown
• Familiarity with electronic DNA/RNA/protein analysis tools, both web-based and software-based (i.e. Lasergene, Vector NTI, etc.)
• Understanding of experimental design and statistical analysis
• Excellent writing and oral communication skills, particularly as they pertain to presentation of experimental findings
• Familiarity with animal models, animal handling and dosing experience is a plus
Interested candidates should send their CV to HR@dicerna.com; please reference Job Code 08200801 in the email subject line when applying for this position.

Dicerna Pharmaceuticals, Inc. is an Equal Opportunity Employer and as such considers qualified individuals without regard to race, color, religion, sex, sexual preference, age, national origin, or disability.

How to Apply

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